The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

Jan. 28, 2009
Applicants:

Scott K. Dessain, Wynnewood, PA (US);

Sharad P. Adekar, Secane, PA (US);

Inventors:

Scott K. Dessain, Wynnewood, PA (US);

Sharad P. Adekar, Secane, PA (US);

Assignee:

Thomas Jefferson University, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/06 (2006.01); C12N 5/00 (2006.01); C07K 16/12 (2006.01); C12N 5/16 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1282 (2013.01); C12N 5/163 (2013.01); C07K 2316/96 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/92 (2013.01); C12N 2501/23 (2013.01); C12N 2501/52 (2013.01); C12N 2510/02 (2013.01);
Abstract

This invention relates to a novel hybridoma strategy that uses CD27+ B cells cultured in vitro to induce IgM to IgG class switch prior to fusion with a fusion partner. Hybridomas resulting from the fusion between CD27+ B cells and a fusion partner cell line and antibodies secreted from the hybridomas are included in the invention.


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Dessain, Scott. (2015). Method of making hybrid cells that express useful antibodies (U.S. Patent No. 8999707). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8999707

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