The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
Aug. 13, 2012
David M. Sabatini, Cambridge, MA (US);
Do-hyung Kim, Minneapolis, MN (US);
Dos D. Sarbassov, Shrewsbury, MA (US);
David M. Sabatini, Cambridge, MA (US);
Do-Hyung Kim, Minneapolis, MN (US);
Dos D. Sarbassov, Shrewsbury, MA (US);
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Abstract
The invention describes isolated mTOR-associated proteins ('mTOR-APs') as well as isolated variants and fragments thereof and the isolated nucleic acids encoding them. The invention also describes vectors and host cells containing nucleic acid encoding an mTOR-AP polypeptide and methods for producing an mTOR-AP polypeptide. Also described are methods for screening for compounds which modulate mTOR-AP activity and methods for treating or preventing a disorder that is responsive to mTOR-AP modulation.