The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

May. 25, 2007
Applicants:

Subramanian Venkatraman, Singapore, SG;

Yin Chiang Boey, Singapore, SG;

Inventors:

Subramanian Venkatraman, Singapore, SG;

Yin Chiang Boey, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/28 (2006.01); A61L 29/08 (2006.01); A61L 31/08 (2006.01); A61F 2/04 (2013.01); A61F 2/06 (2013.01); A61F 2/00 (2006.01); A61L 27/58 (2006.01); A61L 27/34 (2006.01); A61L 31/10 (2006.01); A61L 27/18 (2006.01); A61L 27/50 (2006.01); A61L 27/56 (2006.01); A61L 33/00 (2006.01);
U.S. Cl.
CPC ...
A61F 2/0077 (2013.01); A61L 27/58 (2013.01); A61L 29/08 (2013.01); A61L 27/34 (2013.01); A61L 31/10 (2013.01); A61L 31/08 (2013.01); A61L 2420/06 (2013.01); A61L 2420/08 (2013.01); A61F 2/06 (2013.01); A61F 2210/0004 (2013.01); A61L 27/18 (2013.01); A61L 27/50 (2013.01); A61L 27/56 (2013.01); A61L 33/0011 (2013.01); A61L 2400/18 (2013.01);
Abstract

Endothelialization of a bodily fluid or tissue-contacting, particularly blood-contacting, surface may be accomplished to render that surface substantially non-thrombogenic. Thrombosis may also be mitigated or eliminated by providing an eroding layer on the surface that results in the removal of any thrombus formation as the layer erodes. An implantable device may utilize at least one surface having a plurality of nano-craters thereon that enhance or promote endothelialization. Additionally, an implantable device may have at least one first degradable layer for contacting bodily fluid or tissue and disposed about a central core, and at least one second degradable layer between the first degradable layer and the central core. The first degradable layer has a first degradation rate and the second degradable layer has a second degradation rate which degrades more slowly than the first degradable layer on contact with bodily fluid or tissue.


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