The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2015
Filed:
Mar. 01, 2011
Applicant:
Cynthia Magro, New York, NY (US);
Inventor:
Cynthia Magro, New York, NY (US);
Assignee:
Alexion Pharmaceuticals, Inc., Cheshire, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 14/00 (2006.01); A61K 38/17 (2006.01); A61K 31/245 (2006.01); A61K 38/12 (2006.01); A61K 45/06 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1725 (2013.01); A61K 31/245 (2013.01); A61K 38/12 (2013.01); A61K 45/06 (2013.01); C07K 16/18 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01); C07K 2317/34 (2013.01);
Abstract
The present disclosure relates to, inter alia, compositions containing an inhibitor of human complement and/or an inhibitor of interferon alpha, and the use of the compositions in methods for treating or preventing Degos' disease in a subject. In some embodiments, the inhibitor is an antibody, or antigen-binding fragment thereof, that binds to a human complement component C5 protein or to a biologically-active fragment of C5 such as C5a or C5b. In some embodiments, the inhibitor is an antibody, or an antigen-binding fragment thereof, that binds to interferon alpha or to an interferon alpha receptor.