The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

Mar. 26, 2013
Applicant:

Viventia Bio Inc., Winnipeg, CA;

Inventors:

Francina C. Chahal, Winnipeg, CA;

Jeannick Cizeau, Winnipeg, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); G01N 33/574 (2006.01); A61K 47/48 (2006.01); C07K 14/21 (2006.01); C07K 16/18 (2006.01); C07K 16/30 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 47/48469 (2013.01); A61K 47/48538 (2013.01); A61K 47/48569 (2013.01); A61K 2039/505 (2013.01); C07K 14/21 (2013.01); C07K 16/18 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/77 (2013.01); G01N 33/5023 (2013.01); G01N 33/57496 (2013.01);
Abstract

The present application provides the amino acid and nucleic acid sequences of heavy and light chain complementarity determining regions of a cancer specific antibody directed to an epitope of variant Nuclear Factor Kappa-B inhibitor beta (NFKBIB). In addition, the application provides cancer specific antibodies and immunoconjugates comprising the cancer specific antibody attached to a toxin or a label, and methods of uses thereof. The application also relates to diagnostic methods and kits using the cancer specific antibodies herein. Further, the application provides novel cancer-associated epitopes and antigens of variant NFKBIB, and uses thereof.


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