The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2015

Filed:

Mar. 12, 2013
Applicant:

Ondavia, Inc., Hayward, CA (US);

Inventors:

Mark C. Peterman, Fremont, CA (US);

Merwan Benhabib, San Francisco, CA (US);

Benjamin A. Obrock, San Francisco, CA (US);

Assignee:

OndaVia, Inc., Hayward, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/65 (2006.01); B01L 3/00 (2006.01); B01D 57/02 (2006.01); B01D 61/42 (2006.01);
U.S. Cl.
CPC ...
G01N 21/658 (2013.01); B01L 3/502761 (2013.01); B01D 57/02 (2013.01); B01D 61/427 (2013.01);
Abstract

A microfluidic separation device is provided that includes a first sample channel region and a second sample channel region, where the first sample channel region has an array of channels that are smaller than the second channel region, a first detection region and a second detection region located at the interface of the first sample channel region, a detection channel, an illuminating electric field, Raman-scattering nanoparticles having surface plasmon resonances for detection when illuminated by the electric field, where the resonances create an enhanced local electric field along specific directions resulting in an enhanced Raman response, and a nanoparticle input channel disposed to input the nanoparticles into the second sample channel region, where the nanoparticles are larger than the cross-section of the first sample channel region and the cross-section of the second detection region, where the nanoparticles collect in the first detection region to form region of densely packed nanoparticles.


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