The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Apr. 17, 2013
General Electric Company, Schenectady, NY (US);
Alberto Santamaria-Pang, Schenectady, NY (US);
Jens Rittscher, Niskayuna, NY (US);
Dirk Padfield, Niskayuna, NY (US);
Ali Can, Niskayuna, NY (US);
Zhengyu Pang, Niskayuna, NY (US);
Musodiq Bello, Niskayuna, NY (US);
Fiona Ginty, Niskayuna, NY (US);
Christopher Sevinsky, Watervliet, NY (US);
Qing Li, Niskayuna, NY (US);
Megan Rothney, Madison, WI (US);
Brion Sarachan, Schenectady, NY (US);
General Electric Company, Niskayuna, NY (US);
Abstract
Improved systems and methods for the analysis of digital images are provided. More particularly, the present disclosure provides for improved systems and methods for the analysis of digital images of biological tissue samples. Exemplary embodiments provide for: i) segmenting, ii) grouping, and iii) quantifying molecular protein profiles of individual cells in terms of sub cellular compartments (nuclei, membrane, and cytoplasm). The systems and methods of the present disclosure advantageously perform tissue segmentation at the sub-cellular level to facilitate analyzing, grouping and quantifying protein expression profiles of tissue in tissue sections globally and/or locally. Performing local-global tissue analysis and protein quantification advantageously enables correlation of spatial and molecular configuration of cells with molecular information of different types of cancer.