The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Nov. 24, 2009
Manjinder Singh Phull, Maharashtra, IN;
Rajendra Narayanrao Kankan, Maharashtra, IN;
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Ashwini Amol Sawant, Maharashtra, IN;
Sanoj Thoppil, Maharashtra, IN;
Manjinder Singh Phull, Maharashtra, IN;
Rajendra Narayanrao Kankan, Maharashtra, IN;
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Ashwini Amol Sawant, Maharashtra, IN;
Sanoj Thoppil, Maharashtra, IN;
Cipla Limited, Mumbai, IN;
Abstract
The present invention provides a process for preparing methyl 5-acetamido-4-amino-6-(1,2,3-triacetoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylate (V), which process comprises reducing methyl 5-acetamido-4-azido-6-(1,2,3-triacetoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylate (IV) in the presence of a reducing agent selected from the group consisting of lithium aluminum hydride, sodium borohydride, zinc/ammonium chloride, zinc-ferric chloride and ferric chloride/sodium iodide. The present invention also provides compounds of formula (VIII) and (IX) which may be used in the synthesis of zanamivir. The present invention also provides processes for preparing compounds (VIII) and (IX) and processes involving their use, including in the synthesis of zanamivir.