The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Sep. 14, 2012
Sun Joon Min, Seoul, KR;
Yong Seo Cho, Seoul, KR;
Jae Kyun Lee, Seoul, KR;
AE Nim Pae, Seoul, KR;
Young Wook Son, Gyeonggi-do, KR;
Sun Joon Min, Seoul, KR;
Yong Seo Cho, Seoul, KR;
Jae Kyun Lee, Seoul, KR;
Ae Nim Pae, Seoul, KR;
Young Wook Son, Gyeonggi-do, KR;
Korea Institute of Science and Technology, Seoul, KR;
Abstract
The present invention relates to a method for preparing tetrabenazine (TBZ) and dihydrotetrabenazine (DTBZ), and more specifically to a method for preparing tetrabenazine (TBZ) and dihydrotetrabenazine (DTBZ) by using simple and short reaction processes of using 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 4-methyl-2-(3-(trimethylsilyl)prop-1-ene-2-yl)pentane as starting materials to sequentially perform an alkylation reaction, an Aza-Prins cyclization reaction in the presence of an oxidant and an oxidation reaction.