The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Jan. 14, 2014
Applicants:

Markus Ostermeier, Biberach an der Riss, DE;

Juergen Daeubler, Ummendorf, DE;

Guenther Huchler, Hochdorf, DE;

Stephan Kling, Warthausen, DE;

Marco Santagostino, Mittelbiberach, DE;

Inventors:

Markus Ostermeier, Biberach an der Riss, DE;

Juergen Daeubler, Ummendorf, DE;

Guenther Huchler, Hochdorf, DE;

Stephan Kling, Warthausen, DE;

Marco Santagostino, Mittelbiberach, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/72 (2006.01); C07D 403/12 (2006.01); C07D 239/70 (2006.01); C07D 241/38 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 239/70 (2013.01); C07D 241/38 (2013.01);
Abstract

The present invention relates to a process for the stereoselective preparation of compounds of formulae (1A) and (1B) and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for the treatment of diseases, particularly tumoral diseases as well as benign prostatic hyperplasia (BPH), diseases of the lungs and airways.


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