The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Jun. 04, 2012
Applicants:
Arie Abo, Oakland, CA (US);
Wouter Korver, Menlo Park, CA (US);
Inventors:
Arie Abo, Oakland, CA (US);
Wouter Korver, Menlo Park, CA (US);
Assignees:
Nuvelo, Inc., San Carlos, CA (US);
ARCA BioPharma, Inc., Westminster, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); C07K 16/2803 (2013.01); G01N 33/57426 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2299/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/92 (2013.01);
Abstract
Anti-NTB-A antibodies and antigen-binding fragments thereof, as well as pharmaceutical compositions comprising such antibodies and antigen-binding fragments are described. Also described are methods of using such antibodies and antigen-binding regions to bind NTB-A and treat diseases, such as hematologic malignancies, which are characterized by expression of NIB-A.