The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

May. 10, 2012
Applicants:

R. Scott Bitner, Pleasant Prairie, WI (US);

Kaitlin E. Browman, Deerfield, IL (US);

Michael E. Brune, Mundelein, IL (US);

Steven Fung, Mount Prospect, IL (US);

Peer B. Jacobson, Libertyville, IL (US);

Lynne E. Rueter, Round Lake Beach, IL (US);

Marina I. Strakhova, Vernon Hills, IL (US);

Jiahong Wang, Lake Bluff, IL (US);

Jeffrey J. Rohde, Evanston, IL (US);

Qi Shuai, Dekalb, IL (US);

James T. Link, Stanford, CA (US);

Jyoti R. Patel, Libertyville, IL (US);

Jurgen Dinges, Wadsworth, IL (US);

Bryan K. Sorensen, Antioch, IL (US);

Hong Yong, Libertyville, IL (US);

Vince S. Yeh, San Diego, CA (US);

Ravi Kurukulasuriya, East Lyme, CT (US);

Inventors:

R. Scott Bitner, Pleasant Prairie, WI (US);

Kaitlin E. Browman, Deerfield, IL (US);

Michael E. Brune, Mundelein, IL (US);

Steven Fung, Mount Prospect, IL (US);

Peer B. Jacobson, Libertyville, IL (US);

Lynne E. Rueter, Round Lake Beach, IL (US);

Marina I. Strakhova, Vernon Hills, IL (US);

Jiahong Wang, Lake Bluff, IL (US);

Jeffrey J. Rohde, Evanston, IL (US);

Qi Shuai, Dekalb, IL (US);

James T. Link, Stanford, CA (US);

Jyoti R. Patel, Libertyville, IL (US);

Jurgen Dinges, Wadsworth, IL (US);

Bryan K. Sorensen, Antioch, IL (US);

Hong Yong, Libertyville, IL (US);

Vince S. Yeh, San Diego, CA (US);

Ravi Kurukulasuriya, East Lyme, CT (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/16 (2006.01); C07C 233/11 (2006.01); A61K 31/165 (2006.01); A61K 31/195 (2006.01); A61K 31/44 (2006.01); A61K 31/45 (2006.01); A61K 31/5377 (2006.01); C07C 233/52 (2006.01); C07C 233/58 (2006.01); C07C 233/63 (2006.01); C07C 237/24 (2006.01); C07C 311/46 (2006.01); C07D 207/277 (2006.01); C07D 211/78 (2006.01); C07D 213/56 (2006.01); C07D 231/12 (2006.01); C07D 261/08 (2006.01); C07D 333/24 (2006.01);
U.S. Cl.
CPC ...
C07C 233/11 (2013.01); A61K 31/165 (2013.01); A61K 31/195 (2013.01); A61K 31/44 (2013.01); A61K 31/45 (2013.01); A61K 31/5377 (2013.01); C07C 233/52 (2013.01); C07C 233/58 (2013.01); C07C 233/63 (2013.01); C07C 237/24 (2013.01); C07C 311/46 (2013.01); C07D 207/277 (2013.01); C07D 211/78 (2013.01); C07D 213/56 (2013.01); C07D 231/12 (2013.01); C07D 261/08 (2013.01); C07D 333/24 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01); C07C 2103/74 (2013.01);
Abstract

The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.


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