The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Mar. 05, 2013
Applicant:
Hoffmann-la Roche Inc., Newark, NJ (US);
Inventors:
David Joseph Bartkovitz, Nutley, NJ (US);
Xin-Jie Chu, Shanghai, CN;
Binh Thanh Vu, North Caldwell, NJ (US);
Chunlin Zhao, Shanghai, CN;
Daniel Fishlock, Basel, CH;
Assignee:
F. Hoffmann-La Roche AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/38 (2006.01); A61K 31/40 (2006.01); C07D 403/12 (2006.01); C07D 207/16 (2006.01); C07F 9/572 (2006.01); C07H 15/26 (2006.01); C07D 405/12 (2006.01); C07D 493/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 207/16 (2013.01); C07F 9/572 (2013.01); C07H 15/26 (2013.01); C07D 405/12 (2013.01); C07D 493/04 (2013.01); C07F 9/5727 (2013.01);
Abstract
There are provided compounds of the formula wherein X, Y, Z, R, R, Rand Rare as described hereinand enantiomers and pharmaceutically acceptable salts and esters thereof. The compounds are useful as anticancer agents.