The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Jan. 09, 2012
Applicants:
Don Benjamin, Basel, CH;
Marco Colombi, Basel, CH;
Michael Hall, Basel, CH;
Christoph Moroni, Basel, CH;
Inventors:
Don Benjamin, Basel, CH;
Marco Colombi, Basel, CH;
Michael Hall, Basel, CH;
Christoph Moroni, Basel, CH;
Assignee:
Universitat Basel, Basel, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 31/155 (2006.01); A61K 31/35 (2006.01); A61K 31/4375 (2006.01); A61K 31/4745 (2006.01); A61K 31/625 (2006.01); A61K 31/7072 (2006.01); A61K 31/365 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4375 (2013.01); A61K 45/06 (2013.01); A61K 31/155 (2013.01); A61K 31/35 (2013.01); A61K 31/4745 (2013.01); A61K 31/625 (2013.01); A61K 31/7072 (2013.01); A61K 31/365 (2013.01);
Abstract
The invention relates to a combination of syrosingopine and a mitochondrial inhibitor, e.g. metformin or oligomycin, and the use of the combination of syrosingopine and a mitochondrial inhibitor for the treatment of cancer and for achieving immunosuppression. The invention also relates to a fluorescence-based method for predicting syrosingopine sensitivity of a cancer cell.