The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Nov. 26, 2013
Applicant:

Ab Science, Paris, FR;

Inventors:

Marco Ciufolini, Vancouver, CA;

Camille Wermuth, Srasbourg, FR;

Bruno Giethlen, Altofr, FR;

Alain Moussy, Paris, FR;

Assignee:

AB Science, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/04 (2006.01); C07D 277/42 (2006.01); C07D 417/14 (2006.01); C07D 277/56 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); C07D 277/42 (2013.01); C07D 277/56 (2013.01); C07D 417/14 (2013.01);
Abstract

Novel compounds selected from 2-(3-aminoaryl)amino-4-aryl-thiazoles of formula (I) that selectively modulate, regulate, and/or inhibit signal transductions mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative metabolic, allergic and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.


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