The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Dec. 20, 2011
Applicants:

Elisabeth Dupont-passelaigue, Colomiers, FR;

Isabelle Le Roy, Frouzins, FR;

Samuel Mialhe, Castres, FR;

Christophe Pignier, Castres, FR;

Inventors:

Elisabeth Dupont-Passelaigue, Colomiers, FR;

Isabelle Le Roy, Frouzins, FR;

Samuel Mialhe, Castres, FR;

Christophe Pignier, Castres, FR;

Assignee:

Pierre Fabre Medicament, Boulogne-Billancourt, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/58 (2006.01); A61K 31/50 (2006.01); C07D 237/00 (2006.01); C07D 237/02 (2006.01); C07D 237/14 (2006.01); C07D 231/20 (2006.01);
U.S. Cl.
CPC ...
C07D 237/14 (2013.01); C07D 231/20 (2013.01);
Abstract

The present invention relates to diarylpyridazinone derivatives that block the potassium Kv channels (specifically the Kv1.5, Kv4.3, and Kv11.1 channels) and to the use thereof for the treatment of humans. Said compounds have the general formula (I), where Rand Rare simultaneously or independently one or more groupings such as: halogen, such as F, Br, Cl, a straight or branched C-Calkyl, hydroxy, a straight or branched C-Calkoxy, arylsulfonamido, in which the aryl is optionally replaced with a straight or branched C-Calkyl, or nitrile, as well as the various enantiomers and the mixtures thereof in any proportion, and the pharmaceutically acceptable salts thereof.


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