The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Apr. 16, 2010
Applicants:

Maria Gabriella Brasca, Cusago, IT;

Elena Casale, Somma Lombardo, IT;

Ron Ferguson, Scotch Plains, NJ (US);

Paolo Polucci, Cassina Rizzardi, IT;

Fabio Zuccotto, Milan, IT;

Inventors:

Maria Gabriella Brasca, Cusago, IT;

Elena Casale, Somma Lombardo, IT;

Ron Ferguson, Scotch Plains, NJ (US);

Paolo Polucci, Cassina Rizzardi, IT;

Fabio Zuccotto, Milan, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/14 (2006.01); C07D 261/14 (2006.01); C07D 261/18 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 453/02 (2006.01); A61K 31/42 (2006.01); A61K 31/454 (2006.01); A61K 31/439 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 231/14 (2013.01); C07D 261/14 (2013.01); C07D 261/18 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 453/02 (2013.01);
Abstract

The present invention relates to substituted resorcinol derivatives which inhibit the activity of Heat Shock Protein HSP90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, pharmaceutical compositions comprising them, methods of treating diseases and the pharmaceutical compositions comprising these compounds.


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