The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Dec. 10, 2010
Applicants:
Abraham Brass, Newton, MA (US);
Stephen Elledge, Brookline, MA (US);
Inventors:
Abraham Brass, Newton, MA (US);
Stephen Elledge, Brookline, MA (US);
Assignees:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 5/22 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); C12N 7/00 (2006.01); A61K 38/17 (2006.01); A61K 39/155 (2006.01); C07K 14/705 (2006.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 38/17 (2013.01); A61K 39/155 (2013.01); C07K 14/705 (2013.01); C12Q 1/18 (2013.01); A01K 2217/052 (2013.01); A01K 2217/075 (2013.01); A01K 2267/02 (2013.01); A01K 2267/0337 (2013.01); C12N 2740/13051 (2013.01); C12N 2760/10051 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/20251 (2013.01); C12N 2770/24051 (2013.01); C12N 2770/24151 (2013.01);
Abstract
The use of interferon induced transmembrane protein 1, 2, or 3 (IFITM1, 2, or 3) as a viral restriction factor, and methods of using the same to produce virus, transgenic animals expressing exogenous IFITM1, 2, or 3, and methods of treating or inhibiting viral infections by targeting a gene identified herein.