The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Mar. 31, 2014
Applicant:

Johann Wolfgang Goethe—universitaet Frankfurt AM Main, Frankfurt am Main, DE;

Inventors:

Eckhard Boles, Darmstadt, DE;

Beate Rother, Einbeck, DE;

Assignee:

Butalco GmbH, Hünenberg, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/90 (2006.01); C12N 15/00 (2006.01); C12N 1/14 (2006.01); C07H 21/04 (2006.01); C07H 21/00 (2006.01); C12N 9/00 (2006.01); C12N 15/81 (2006.01); C12P 7/10 (2006.01); C12N 1/18 (2006.01);
U.S. Cl.
CPC ...
C07H 21/00 (2013.01); C12N 9/00 (2013.01); C12N 15/81 (2013.01); C12P 7/10 (2013.01); C12N 1/18 (2013.01); C12N 15/00 (2013.01); Y02E 50/16 (2013.01); Y02E 50/17 (2013.01);
Abstract

The present invention relates to novel expression cassettes and expression vectors, comprising three nucleic acid sequences for araA, araB and araD, each coding for a polypeptide of an L-arabinose metabolic pathway, in particular, a bacterial L-arabinose metabolic pathway. The invention particularly relates to expression cassettes and expression vectors, comprising codon-optimized nucleic acid sequences for araA, araB and araD. The invention further relates to host cells, in particular modified yeast strains containing the expression cassettes or expression vectors and expressing the polypeptides for the L-arabinose metabolic pathway, in particular, for the bacterial L-arabinose metabolic pathway. When using these modified host cells, arabinose is more effectively fermented by these cells, in particular into ethanol. The present invention is therefore relevant, inter alia, in connection with the production of biochemicals from biomass, such as bioethanol for example.


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