The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Jun. 03, 2013
Ping Yan, Middletown, CT (US);
Corey D. Acker, West Hartford, CT (US);
Leslie M. Loew, West Hartford, CT (US);
Ping Yan, Middletown, CT (US);
Corey D. Acker, West Hartford, CT (US);
Leslie M. Loew, West Hartford, CT (US);
The University of Connecticut, Farmington, CT (US);
Abstract
A fluorinated voltage sensitive dye has the structure wherein p is 0, 1, or 2; Xis an anionic counterion having a charge, q, that is 1 or 2; n is 1 or 2; Ris an optionally substituted C-C, alkyl; Ris hydrogen, and Ris hydrogen or fluorine; or Rand Rcollectively form a divalent —CH═CH—CH═CH— group; Rand each occurrence of Rare each independently hydrogen or fluorine; Ris hydrogen or fluorine or trifluoromethyl; and each occurrence of Ris independently C-Calkyl;provided that the dye comprises at least one fluorine atom. The dye is particularly useful for monitoring the dynamics of action potentials in axons and/or dendrites.