The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

May. 04, 2010
Applicants:

Mu-yi Hua, Tao-Yuan, TW;

Hung-wei Yang, Tao-Yuan, TW;

Rung-ywan Tsai, Kaohsiung, TW;

Kuo-chen Wei, Taipei, TW;

Pin-yuan Chen, Taipei, TW;

Chiung-yin Huang, Yangmei Township, Taoyuan County, TW;

Inventors:

Mu-Yi Hua, Tao-Yuan, TW;

Hung-Wei Yang, Tao-Yuan, TW;

Rung-Ywan Tsai, Kaohsiung, TW;

Kuo-Chen Wei, Taipei, TW;

Pin-Yuan Chen, Taipei, TW;

Chiung-Yin Huang, Yangmei Township, Taoyuan County, TW;

Assignee:

Chang Gung University, Kwei-Shan, Tao-Yuan, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A01N 47/34 (2006.01); A61K 31/17 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48861 (2013.01);
Abstract

The present invention discloses a magnetic nanocomposite for inhibiting/treating cancer and a method for fabricating the same. The magnetic nanocomposite comprises a core formed of a plurality of magnetic nanoparticles made of ferric ferrous oxide (FeO); a shell made of a carboxy-functionalized polyaniline; and an anti-tumor medicine bound to the external surface of the shell. The method of the present invention fast fabricates the magnetic nanocomposite in a simple way. The medicine of the present invention has a longer half life and a better thermal stability. The present invention disperses the water-insoluble medicine in water uniformly to decrease the biological rejection. Moreover, the magnetic nanocomposite of the present invention is guided to the nidus by an external magnetic field to increase the local concentration of the medicine and provide an effective chemotherapy. Therefore, the present invention has competitive advantage over the conventional BCNU.


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