The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Oct. 21, 2010
C. Jeffrey Brinker, Albuquerque, NM (US);
Carlee Erin Ashley, Albuquerque, NM (US);
Xingmao Jiang, Albuquerque, NM (US);
Juewen Liu, Kitchener, CA;
David S. Peabody, Albuquerque, NM (US);
Walker Richard Wharton, Corrales, NM (US);
Eric Carnes, Albuquerque, NM (US);
Bryce Chackerian, Albuquerque, NM (US);
Cheryl L. Willman, Albuquerque, NM (US);
C. Jeffrey Brinker, Albuquerque, NM (US);
Carlee Erin Ashley, Albuquerque, NM (US);
Xingmao Jiang, Albuquerque, NM (US);
Juewen Liu, Kitchener, CA;
David S. Peabody, Albuquerque, NM (US);
Walker Richard Wharton, Corrales, NM (US);
Eric Carnes, Albuquerque, NM (US);
Bryce Chackerian, Albuquerque, NM (US);
Cheryl L. Willman, Albuquerque, NM (US);
STC.UNM, Albuquergue, NM (US);
Sandia Corporation, Albuquerque, NM (US);
Abstract
Various embodiments provide materials and methods for synthesizing protocells for use in targeted delivery of cargo components to cancer cells. In one embodiment, the lipid bilayer can be fused to the porous particle core to form a protocell. The lipid bilayer can be modified with targeting ligands or other ligands to achieve targeted delivery of cargo components that are loaded within the protocell to a target cell, e.g., a type of cancer. Shielding materials can be conjugated to the surface of the lipid bilayer to reduce undesired non-specific binding.