The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Jun. 26, 2008
Applicant:

Agis Kydonieus, Kendall Park, NJ (US);

Inventor:

Agis Kydonieus, Kendall Park, NJ (US);

Assignee:

Samos Pharmaceuticals, LLC, Kendall Park, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 9/0021 (2013.01); A61K 47/481 (2013.01); A61K 47/48123 (2013.01); A61K 9/0009 (2013.01); A61K 9/0043 (2013.01);
Abstract

Compositions and methods for modifying biologically active substances to achieve multi-day delivery of such substances, particularly through oral or parenteral administration, are disclosed. The compositions include the biologically active substance conjugated to a carrier having a suitably long half life, typically more than one day, wherein the conjugate optionally contains a spacer linking the carrier to the biologically active substance. Pharmaceutical formulations of the conjugates are also disclosed, as are methods of extending delivery of a single dose of a biologically active substance for more than one day.


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