The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Apr. 23, 2012
Applicants:

Nancy J. Shelby, Bozeman, MT (US);

Steven M. Scott, Salt Lake City, UT (US);

Benjamin P. Luchsinger, Bozeman, MT (US);

Gregory A. Juda, Bozeman, MT (US);

Kelly R. Kirker, Bozeman, MT (US);

Jesus Hernandez, Bozeman, MT (US);

Darrel L. Holmes, Bozeman, MT (US);

Inventors:

Nancy J. Shelby, Bozeman, MT (US);

Steven M. Scott, Salt Lake City, UT (US);

Benjamin P. Luchsinger, Bozeman, MT (US);

Gregory A. Juda, Bozeman, MT (US);

Kelly R. Kirker, Bozeman, MT (US);

Jesus Hernandez, Bozeman, MT (US);

Darrel L. Holmes, Bozeman, MT (US);

Assignee:

Bacterin International, Inc., Belgrade, MT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/02 (2006.01); A61L 27/36 (2006.01); A61F 2/46 (2006.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3691 (2013.01); A61F 2/4644 (2013.01); A61L 27/3608 (2013.01); A61L 27/3683 (2013.01); A61L 27/3804 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); C12N 5/0068 (2013.01); A61L 2300/414 (2013.01); C12N 2533/90 (2013.01);
Abstract

A demineralized bone matrix is produced by a process in which a bone body is placed in a first processing solution comprising an acid to demineralize the bone body. The bone body is periodically removed from the first solution at specific time intervals to perform at least one test, such as a compression test, on a mechanical property of the bone body. When the test yields a desired result, the bone body is exposed to a second processing solution that is less acidic than the first, thus minimizing the exposure of the bone body to the harsh acidic conditions of the demineralization phase of the process.


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