The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Mar. 13, 2009
Applicant:
Stephen M. Strittmatter, Guilford, CT (US);
Inventor:
Stephen M. Strittmatter, Guilford, CT (US);
Assignee:
Yale University, New Haven, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 31/7088 (2006.01); A61K 51/04 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); A61K 51/0406 (2013.01); C07K 14/705 (2013.01); C07K 16/2863 (2013.01); C07K 2319/30 (2013.01); A61K 38/00 (2013.01);
Abstract
Disclosed are methods of treating chronic nervous system diseases or injuries, e.g., chronic spinal cord injury, using Nogo receptor antagonists, including Nogo receptor-1 (NgR1) polypeptides, Nogo receptor-1 antibodies and antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof, and polynucleotides. Also disclosed are methods of noninvasively monitoring axonal growth during and after treatment with an axonal growth promoting agent.