The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2015

Filed:

Apr. 14, 2014
Applicant:

Canon U.s. Life Sciences, Inc., Rockville, MD (US);

Inventors:

Brian Murphy, Baltimore, MD (US);

Scott Corey, Hydes, MD (US);

Alex Flamm, Baltimore, MD (US);

Ben Lane, Hydes, MD (US);

Conrad Laskowski, Bethesda, MD (US);

Chad Schneider, Owings Mills, MD (US);

Assignee:

Canon U.S. Life Sciences, Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/68 (2006.01); B01L 7/00 (2006.01); G01N 33/50 (2006.01); G01N 21/66 (2006.01); F04B 49/10 (2006.01); H05B 1/02 (2006.01); F04B 49/06 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); G01N 33/50 (2013.01); G01N 21/66 (2013.01); F04B 49/106 (2013.01); B01L 2300/0861 (2013.01); B01L 2200/10 (2013.01); H05B 1/025 (2013.01); F04B 49/065 (2013.01); B01L 3/502715 (2013.01); B01L 7/525 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/141 (2013.01); B01L 2200/147 (2013.01); B01L 2300/18 (2013.01); G01N 2035/00544 (2013.01); B01L 3/502784 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0867 (2013.01); C12Q 2565/629 (2013.01); Y10S 435/808 (2013.01); Y10S 436/805 (2013.01); Y10S 436/809 (2013.01);
Abstract

The present invention relates to systems and methods for minimizing or eliminating diffusion effects. Diffused regions of a segmented flow of multiple, miscible fluid species may be vented off to a waste channel, and non-diffused regions of fluid may be preferentially pulled off the channel that contains the segmented flow. Multiple fluid samples that are not contaminated via diffusion may be collected for analysis and measurement in a single channel. The systems and methods for minimizing or eliminating diffusion effects may be used to minimize or eliminate diffusion effects in a microfluidic system for monitoring the amplification of DNA molecules and the dissociation behavior of the DNA molecules.


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