The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2015
Filed:
Jul. 01, 2010
Philippe Humbert, Ornans, FR;
Delphine Binda, Auxon Dessous, FR;
Celine Viennet-steiner, Ornans, FR;
Sophie Robin, Pirey, FR;
Helene Tauzin, Besancon, FR;
Gwenael Rolin, Besancon, FR;
Lionel Pazart, Besancon, FR;
Philippe Humbert, Ornans, FR;
Delphine Binda, Auxon Dessous, FR;
Celine Viennet-Steiner, Ornans, FR;
Sophie Robin, Pirey, FR;
Helene Tauzin, Besancon, FR;
Gwenael Rolin, Besancon, FR;
Lionel Pazart, Besancon, FR;
Universite de Franche-Comte, Besancon, FR;
Centre Hospitalier Universitaire de Besancon, Besancon, FR;
Abstract
The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.