The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Aug. 14, 2012
Applicants:

Mordechay Schlesinger, Windsor, CA;

Long Jian Liu, Windsor, CA;

James R. Ewing, Detroit, MI (US);

Stephen L. Brown, Detroit, MI (US);

Inventors:

Mordechay Schlesinger, Windsor, CA;

Long Jian Liu, Windsor, CA;

James R. Ewing, Detroit, MI (US);

Stephen L. Brown, Detroit, MI (US);

Assignees:

University of Windsor, Windor, Ontario, CA;

Henry Ford Hospital, Detroit, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/03 (2006.01); A61B 5/055 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/03 (2013.01); A61B 5/0059 (2013.01);
Abstract

A scanning apparatus, is used to effect multiple images of a tumor in which a contrast agent has been localized as a detectable marker over a selected time to map the change in the imaged marker. The rate of change in the imaged marker and/or contrast intensity of the dyed tissues is used to assess tumor aggressiveness and as an early predictor of response to cancer therapy. In particular, following the marking of tumor or cancerous tissues by the initial localization of an imageable contrast agent, the rate of change in the volume and/or area of the imaged marker is used to provide an indication of tumor interstitial fluid pressure (TIFP).


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