The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Apr. 28, 2014
Applicant:

Laboratori Baldacci Spa, Pisa, IT;

Inventors:

Massimo Baldacci, Pisa, IT;

Marinella Roberti, Bologna, IT;

Assignee:

Laboratori Baldacci SpA, Pisa (PI), IT;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/76 (2006.01); C07C 227/02 (2006.01); C07C 229/66 (2006.01); C07D 303/12 (2006.01);
U.S. Cl.
CPC ...
C07C 227/02 (2013.01); C07C 229/66 (2013.01); C07D 303/12 (2013.01);
Abstract

The present invention concerns a new process for the synthesis of aminaphtone, which makes use of non-toxic solvents and reagents, under mild reaction and temperature conditions. The aminaphtone obtained with the method of the present invention also has a purity of at least 98% in weight. The method comprises the following steps: a) epoxidating menadione 1 to provide epoxide 2, b) acidifying epoxide 2 to provide hydroxynaphthoquinone 3, c) esterifying between hydroxynaphthoquinone 3 and 4-aminobenzoyl chloride to obtain compound 4, and d) reducing compound 4 in the presence of a reducing agent in water to obtain aminaphtone.


Find Patent Forward Citations

Loading…