The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Nov. 01, 2011
Applicants:

Munekazu Iinuma, Gifu, JP;

Shoei Furukawa, Gifu, JP;

Mitsuru Naiki, Kato, JP;

Tomonori Matsumoto, Kato, JP;

Hachiro Sugimoto, Kyoto, JP;

Inventors:

Munekazu Iinuma, Gifu, JP;

Shoei Furukawa, Gifu, JP;

Mitsuru Naiki, Kato, JP;

Tomonori Matsumoto, Kato, JP;

Hachiro Sugimoto, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 57/02 (2006.01); A61K 31/231 (2006.01); C07C 327/30 (2006.01); C07C 217/08 (2006.01); C07C 219/20 (2006.01); C07C 233/09 (2006.01); C07C 233/38 (2006.01); C07C 327/22 (2006.01); C07C 69/533 (2006.01); C07C 219/08 (2006.01); C07C 323/12 (2006.01); C07D 295/13 (2006.01);
U.S. Cl.
CPC ...
C07C 327/30 (2013.01); A61K 31/231 (2013.01); C07C 57/02 (2013.01); C07C 217/08 (2013.01); C07C 219/20 (2013.01); C07C 233/09 (2013.01); C07C 233/38 (2013.01); C07C 327/22 (2013.01); C07C 2101/08 (2013.01); C07C 69/533 (2013.01); C07C 219/08 (2013.01); C07C 323/12 (2013.01); C07D 295/13 (2013.01); C07C 2101/14 (2013.01);
Abstract

An object of the present invention is to provide a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof and to provide a pharmaceutical agent which contains said compound as an active ingredient and has a highly safe neurotrophic factor-like activity or an alleviating action for side effect induced by administration of anti-cancer agents. The trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof which is the compound of the present invention is specifically represented by the formula (1): (In the formula, Y is —O—, —NR— or —S—, R is hydrogen atom, alkyl group, dialkylaminoalkyl group or the like and W is a substituent such as dialkylaminoalkyl group) and has a quite high usefulness as a pharmaceutical agent such as a preventive or therapeutic agent for dementia, Alzheimer's disease, Parkinson's disease, depression, etc., a treating or repairing agent for spinal cord injury.


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