The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Mar. 24, 2009
Applicants:
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Rajendra Narayanrao Kankan, Maharashtra, IN;
Srinivas Laxminarayan Pathi, Karnataka, IN;
Inventors:
Dharmaraj Ramachandra Rao, Maharashtra, IN;
Rajendra Narayanrao Kankan, Maharashtra, IN;
Srinivas Laxminarayan Pathi, Karnataka, IN;
Assignee:
Cipla Limited, Mumbai, IN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/02 (2006.01); C07D 213/20 (2006.01); C07D 211/32 (2006.01);
U.S. Cl.
CPC ...
C07D 213/20 (2013.01); C07D 211/32 (2013.01);
Abstract
The present invention provides a process for preparing donepezil or a salt thereof, the process comprising reducing a 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methylene]pyridonium halide of formula II, wherein X is bromide or chloride, in the presence of an ionic compound, a solvent, a catalyst and a source of hydrogen, to form donepezil and optionally converting the donepezil to the salt thereof.