The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Mar. 21, 2013
Applicant:
Sloan-kettering Institute for Cancer Research, New York, NY (US);
Inventors:
Ouathek Ouerfelli, Fort Lee, NJ (US);
Anna Dilhas, Basel, CH;
Guangbin Yang, Forest Hills, NY (US);
Hong Zhao, Rego Park, NY (US);
Assignee:
Sloan-Kettering Institute for Cancer Research, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07C 209/36 (2006.01); C07C 213/08 (2006.01); C07C 253/00 (2006.01); C07C 253/30 (2006.01); C07D 213/61 (2006.01); C07D 213/64 (2006.01); C07D 213/72 (2006.01); C07D 213/74 (2006.01); C07D 213/84 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); C07C 209/36 (2013.01); C07C 213/08 (2013.01); C07C 253/00 (2013.01); C07C 253/30 (2013.01); C07D 213/61 (2013.01); C07D 213/64 (2013.01); C07D 213/72 (2013.01); C07D 213/74 (2013.01); C07D 213/84 (2013.01); C07C 2101/04 (2013.01);
Abstract
A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52.