The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Sep. 24, 2009
Applicants:

William F. Degrado, San Francisco, CA (US);

Meredith W. Miller, Philadelphia, PA (US);

Sandeep Basra, Munich, DE;

Joel S. Bennett, Bryn Mawr, PA (US);

Sungwook Choi, San Diego, CA (US);

Inventors:

William F. DeGrado, San Francisco, CA (US);

Meredith W. Miller, Philadelphia, PA (US);

Sandeep Basra, Munich, DE;

Joel S. Bennett, Bryn Mawr, PA (US);

Sungwook Choi, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/40 (2006.01); A61K 31/445 (2006.01); A01N 43/78 (2006.01); A61K 31/425 (2006.01); A01N 43/36 (2006.01); A61K 31/40 (2006.01); C07D 211/22 (2006.01); C07D 277/00 (2006.01); C07D 207/48 (2006.01); C07D 205/04 (2006.01); C07D 211/96 (2006.01); C07D 215/58 (2006.01); C07D 217/26 (2006.01); C07D 277/06 (2006.01); C07K 5/078 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07D 207/48 (2013.01); C07D 205/04 (2013.01); C07D 211/96 (2013.01); C07D 215/58 (2013.01); C07D 217/26 (2013.01); C07D 277/06 (2013.01); C07K 5/06165 (2013.01); A61K 38/00 (2013.01);
Abstract

Novel compounds inhibiting the integrin α2β1/GPIa-IIa receptor are disclosed. Also disclosed are pharmaceutical compositions containing the compounds, as well as methods of their therapeutic use. The compounds disclosed are useful, inter alia, as inhibitors of integrin α2β1/GPIa-IIa-mediated activity.


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