The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Feb. 27, 2013
Applicant:
Aptose Biosciences Inc., Toronto, CA;
Inventors:
Raed H. Al-Qawasmeh, North York, CA;
Aiping H. Young, Toronto, CA;
Mario Huesca, Toronto, CA;
Yoon S. Lee, Mississauga, CA;
Assignee:
Aptose Biosciences Inc., Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/444 (2006.01); A61K 31/4439 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); A01N 43/90 (2006.01); A01N 43/50 (2006.01); A01N 43/52 (2006.01); A23L 3/3544 (2006.01); A61K 31/4164 (2006.01); A61K 31/4178 (2006.01); A61K 31/4184 (2006.01); A61K 31/4188 (2006.01); A61L 2/18 (2006.01); C07D 233/22 (2006.01); C07D 235/02 (2006.01); C07D 403/04 (2006.01); C07D 409/14 (2006.01); C07D 471/14 (2006.01); E05B 1/00 (2006.01); A61K 31/4375 (2006.01); A61K 45/06 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
A01N 43/90 (2013.01); A01N 43/50 (2013.01); A01N 43/52 (2013.01); A23L 3/3544 (2013.01); A61K 31/4164 (2013.01); A61K 31/4178 (2013.01); A61K 31/4184 (2013.01); A61K 31/4188 (2013.01); A61L 2/18 (2013.01); C07D 233/22 (2013.01); C07D 235/02 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 409/14 (2013.01); C07D 471/14 (2013.01); E05B 1/0069 (2013.01); A61K 31/4375 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/454 (2013.01); A61K 45/06 (2013.01); C07D 233/64 (2013.01); C07D 401/14 (2013.01);
Abstract
The present invention provides therapeutically effective 2,4,5-trisubstituted imidazole compounds, methods of preparing the same, and compositions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-microbial agents. The anti-microbial properties of the compounds include anti-bacterial and/or anti-fungal activity.