The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Oct. 29, 2013
Oregon Health & Science University, Portland, OR (US);
The United States of America Dba the Department of Veterans Affairs, Washington, DC (US);
Michael K. Riscoe, Tualatin, OR (US);
Rolf W. Winter, Portland, OR (US);
Jane X. Kelly, Portland, OR (US);
David J. Hinrichs, Lake Oswego, OR (US);
Martin J. Smilkstein, Portland, OR (US);
Oregon Health & Science University, Portland, OR (US);
The United States of America DBA The Department of Veterans Affairs, Washington, DC (US);
Abstract
A class of acridone compounds has been discovered that exhibits chemosensitizing and antiparasitic activity. Described herein are pharmaceutical compositions and methods for their use to treat parasitic infections, such as malaria and toxoplasmosis, and to sensitize resistant cells, such as multidrug resistant cells to other therapeutic agents. The pharmaceutical compositions and methods may also be used to treat and/or prevent psychotic diseases such as schizophrenia.