The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Sep. 29, 2009
Applicants:

Christopher Oalmann, Watertown, MA (US);

Robert B. Perni, Marlborough, MA (US);

Chi B. VU, Arlington, MA (US);

Inventors:

Christopher Oalmann, Watertown, MA (US);

Robert B. Perni, Marlborough, MA (US);

Chi B. Vu, Arlington, MA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); A61K 31/5377 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/4025 (2006.01); A61K 31/497 (2006.01); A61K 31/353 (2006.01); A61K 45/06 (2006.01); C07D 311/30 (2006.01); A61P 3/00 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/353 (2013.01); A61K 45/06 (2013.01); C07D 311/30 (2013.01); C07D 405/12 (2013.01); C07D 417/14 (2013.01); C07D 405/14 (2013.01);
Abstract

The present invention relates to novel chromenone analog sirtuin modulator compounds of Formula (I): orpharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods and combination therapies thereof for use in increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity.


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