The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Oct. 18, 2013
Applicant:

Array Biopharma Inc., Boulder, CO (US);

Inventors:

Shelley Allen, Boulder, CO (US);

Laura L. Celeste, Gaithersburg, MD (US);

T. Gregg Davis, Boulder, CO (US);

Robert Kirk DeLisle, Lyons, CO (US);

Julie Marie Hicks, Erie, CO (US);

Stefan D. Gross, Sudbury, MA (US);

Erik James Hicken, Boulder, CO (US);

Leila J. Jackson, Aurora, CO (US);

Nicholas C. Kallan, Louisville, CO (US);

Joseph P. Lyssikatos, Piedmont, CA (US);

Fredrik P. Marmsater, Boulder, CO (US);

Mark C. Munson, Acton, MA (US);

Jed Pheneger, Boulder, CO (US);

Bryson Rast, Westminster, CO (US);

John E. Robinson, Boulder, CO (US);

Stephen T. Schlachter, Dallas, TX (US);

George T. Topalov, Pittsburg, PA (US);

A. Dale Wright, Boulder, CO (US);

Qian Zhao, El Cerrito, CA (US);

Assignee:

Array BioPharma Inc., Boulder, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); C07D 471/04 (2006.01); C07D 451/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 451/06 (2013.01); C07D 519/00 (2013.01); A61K 31/437 (2013.01);
Abstract

Provided herein is a method of treating a PIM-1 and/or PIM-2 and/or PIM-3 kinase-mediated condition in a mammal, which comprises administering to said mammal a therapeutically effective amount of a compound of Formula I: in which A, B, R, R, R, R, R, R, R, and Rhave the meanings given in the specification.


Find Patent Forward Citations

Loading…