The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Jun. 01, 2010
Applicants:

Samuel Chackalamannil, Califon, NJ (US);

Tin-yau Chan, Edison, NJ (US);

Mariappan V. Chelliah, Edison, NJ (US);

Martin C. Clasby, Plainsboro, NJ (US);

Michael Dwyer, Scotch Plains, NJ (US);

William J. Greenlee, Teaneck, NJ (US);

Tomokazu Hirabayashi, Shinjuku-ku, JP;

Santhosh Neelamkavil, Scotch Plains, NJ (US);

Hidemitsu Nishida, Shinjuku-ku, JP;

Fumihiko Saitoh, Shinjuku-ku, JP;

Unmesh Shah, Green Brook, NJ (US);

Yan Xia, Edison, NJ (US);

Inventors:

Samuel Chackalamannil, Califon, NJ (US);

Tin-Yau Chan, Edison, NJ (US);

Mariappan V. Chelliah, Edison, NJ (US);

Martin C. Clasby, Plainsboro, NJ (US);

Michael Dwyer, Scotch Plains, NJ (US);

William J. Greenlee, Teaneck, NJ (US);

Tomokazu Hirabayashi, Shinjuku-ku, JP;

Santhosh Neelamkavil, Scotch Plains, NJ (US);

Hidemitsu Nishida, Shinjuku-ku, JP;

Fumihiko Saitoh, Shinjuku-ku, JP;

Unmesh Shah, Green Brook, NJ (US);

Yan Xia, Edison, NJ (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A01N 43/00 (2006.01); A61K 31/33 (2006.01); C07D 413/12 (2006.01); A61K 31/397 (2006.01); A61K 31/496 (2006.01); A61K 31/5375 (2006.01); A61K 31/5377 (2006.01); A61K 31/54 (2006.01); A61K 31/7088 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07D 265/32 (2006.01); C07D 413/10 (2006.01); C07D 413/14 (2006.01); C07D 417/10 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); A61K 31/397 (2013.01); A61K 31/496 (2013.01); A61K 31/5375 (2013.01); A61K 31/5377 (2013.01); A61K 31/54 (2013.01); A61K 31/7088 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); C07D 265/32 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/10 (2013.01);
Abstract

The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.


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