The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Sep. 26, 2011
Hans-georg Lerchen, Leverkusen, DE;
Sherif El Sheikh, Essen, DE;
Beatrix Stelte-ludwig, Wülfrath, DE;
Sven Golfier, Berlin, DE;
Joachim Schuhmacher, Wuppertal, DE;
Jean Mark Gnoth, Mettmann, DE;
Ursula Krenz, Leichlingen, DE;
Hans-Georg Lerchen, Leverkusen, DE;
Sherif El Sheikh, Essen, DE;
Beatrix Stelte-Ludwig, Wülfrath, DE;
Sven Golfier, Berlin, DE;
Joachim Schuhmacher, Wuppertal, DE;
Jean Mark Gnoth, Mettmann, DE;
Ursula Krenz, Leichlingen, DE;
Seattle Genetics, Inc., Bothell, WA (US);
Abstract
The present application relates to new derivatives of monomethylauristatin F, substituted on the N terminus by a carboxyalkyl group, processes for preparing these derivatives, their use for the treatment and/or prevention of diseases and to produce medication for the treatment and/or prevention of diseases, particularly hyperproliferative and/or angiogenic disorders such as cancer disorders, for example. Such treatments can occur as monotherapies or in combination with other medication or further therapeutic measures.