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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8987203 B1

PDFFull Text
Date of Patent:
Mar. 24, 2015

Filed:

Nov. 16, 2007

Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein

Applicants:

Johannes Petrus Thomas Maria Van Leeuwen, Amstelveen, NL;

Hermanus Johannes Marco Eijken, Rotterdam, NL;

Inventors:

Johannes Petrus Thomas Maria Van Leeuwen, Amstelveen, NL;

Hermanus Johannes Marco Eijken, Rotterdam, NL;

Assignee:

Arcarios B.V., Rotterdam, NL;

Attorney:

Wilson, Sonsini, Goodrich & Rosati, PC

Primary Examiner:

James H Alstrum Acevedo

Assistant Examiner:

Zachary J Miknis

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 19/08 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C12N 5/077 (2010.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0654 (2013.01); A61K 38/17 (2013.01); C12N 2501/16 (2013.01);
Abstract

The present invention relates to methods for selecting a candidate therapeutic agent for controlling mineralization of an extracellular matrix in a tissue of a subject. The invention further relates to a cell culture mineralization model comprising a culture of an extracellular matrix producing cell under conditions that support extracellular matrix formation and matrix maturation, a test compound, and means and methods for determining in expression levels of genes encoding matrix proteins.

Find Patent Forward Citations

Van Leeuwen, Johannes Petrus Thomas Maria. (2015). Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein (U.S. Patent No. 8987203). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8987203

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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