The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Jun. 14, 2006
Applicants:
Jesper Mortensen Haaning, Birkeroed, DK;
Kim Vilbour Andersen, Broenshoej, DK;
Claus Bornaes, Hellerup, DK;
Inventors:
Jesper Mortensen Haaning, Birkeroed, DK;
Kim Vilbour Andersen, Broenshoej, DK;
Claus Bornaes, Hellerup, DK;
Assignee:
Bayer Healthcare LLC, Whippany, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 9/64 (2006.01); A61K 38/48 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6437 (2013.01); A61K 38/4846 (2013.01); C12N 9/647 (2013.01); C12Y 304/21021 (2013.01);
Abstract
Gla domain variants of human Factor VII or human Factor VIIa, comprising 1-15 amino acid modifications relative to the human Factor VII or human Factor VIIa sequence shown in SEQ ID NO:1, wherein a hydrophobic amino acid residue has been introduced by substitution in position 34; or having an amino acid substitution in position 36; and use of the variants for the treatment of intracerebral haemorrhage (ICH) or trauma.