The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Aug. 06, 2013
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Merck Canada Inc., Kirkland, Quebec, CA;

Inventors:

Thomas Bara, Scotch Plains, NJ (US);

Sathesh Bhat, Hoboken, NJ (US);

Dipshikha Biswas, Woodbridge, NJ (US);

Linda Brockunier, Orange, NJ (US);

Duane A. Burnett, Wayland, MA (US);

Samuel Chackalamannil, Califon, NJ (US);

Mariappan V. Chelliah, Edison, NJ (US);

Austin Chen, San Marcos, CA (US);

Martin Clasby, Plainsboro, NJ (US);

Vince J. Colandrea, North Brunswick, NJ (US);

Zhuyan Guo, Scotch Plains, NJ (US);

Yongxin Han, Montreal, CA;

Charles Jayne, Staten Island, NY (US);

Hubert Josien, Jersey City, NJ (US);

Karen Marcantonio, New York, NY (US);

Shouwu Miao, Edison, NJ (US);

Santhosh Neelamkavil, Edison, NJ (US);

Patrick Pinto, Morris Plains, NJ (US);

Murali Rajagopalan, Edison, NJ (US);

Unmesh Shah, Neshanic Station, NJ (US);

Francisco Velazquez, Clinton, NJ (US);

Srikanth Venkatraman, Edison, NJ (US);

Yan Xia, Edison, NJ (US);

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Merck Canada Inc., Kirkland, Quebec, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 5/08 (2006.01); A61K 38/06 (2006.01); A61K 45/06 (2006.01); C07D 491/22 (2006.01); C07D 419/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/08 (2013.01); A61K 38/06 (2013.01); A61K 45/06 (2013.01); C07D 491/22 (2013.01); C07D 419/00 (2013.01);
Abstract

The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.


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