The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Sep. 14, 2012
Nikolay Turovets, Vista, CA (US);
Larisa Agapova, Vista, CA (US);
Andrey Semechkin, Oceanside, CA (US);
Jeffrey Janus, San Diego, CA (US);
Nikolay Turovets, Vista, CA (US);
Larisa Agapova, Vista, CA (US);
Andrey Semechkin, Oceanside, CA (US);
Jeffrey Janus, San Diego, CA (US);
International Stem Cell Corporation, Oceanside, CA (US);
Abstract
The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.