The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Oct. 01, 2008
Stefan Verseck, Hilden, DE;
Steffen Schaffer, Herten, DE;
Werner Freitag, Dorsten, DE;
Friedrich-georg Schmidt, Haltern am See, DE;
Matthias Orschel, Muenster, DE;
Gerda Grund, Coesfeld, DE;
Wilfried Schmidt, Gelsenkirchen-Buer, DE;
Hubert Johannes Bahl, Rostock, DE;
Ralf-joerg Fischer, Kritzmow, DE;
Antje May, Rostock, DE;
Peter Duerre, Ulm, DE;
Simone Lederle, Ulm, DE;
Stefan Verseck, Hilden, DE;
Steffen Schaffer, Herten, DE;
Werner Freitag, Dorsten, DE;
Friedrich-Georg Schmidt, Haltern am See, DE;
Matthias Orschel, Muenster, DE;
Gerda Grund, Coesfeld, DE;
Wilfried Schmidt, Gelsenkirchen-Buer, DE;
Hubert Johannes Bahl, Rostock, DE;
Ralf-Joerg Fischer, Kritzmow, DE;
Antje May, Rostock, DE;
Peter Duerre, Ulm, DE;
Simone Lederle, Ulm, DE;
Evonik Degussa GmbH, Essen, DE;
Abstract
The invention describes a process for preparing acetone starting from acetyl-coenzyme A comprising process steps A. enzymatic conversion of acetyl-CoA into acetoacetyl-CoA B. enzymatic conversion of acetoacetyl-CoA into acetoacetate and CoA and C. decarboxylation of acetoacetate to acetone and CO, which is characterized in that the coenzyme A is not transferred in process step B to an acceptor molecule. In addition, process step B is surprisingly catalyzed by enzymes of the classes of acyl-CoA thioesterase, acyl-CoA synthetase or acyl-CoA thiokinase. A completely novel metabolic pathway is concerned, because the enzymatic hydrolysis of acetoacetyl-CoA without simultaneous transfer of CoA to a receptor molecule has never previously been described for any microbial enzyme.