The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Nov. 04, 2011
Jung Hoon Sohn, Daejeon, KR;
Jung Hoon Bae, Daejeon, KR;
MI Jin Kim, Daejeon, KR;
Hyun Jin Kim, Daejeon, KR;
Soon Ho Park, Daejeon, KR;
Kwang Mook Lim, Daejeon, KR;
Jung Hoon Sohn, Daejeon, KR;
Jung Hoon Bae, Daejeon, KR;
Mi Jin Kim, Daejeon, KR;
Hyun Jin Kim, Daejeon, KR;
Soon Ho Park, Daejeon, KR;
Kwang Mook Lim, Daejeon, KR;
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Abstract
The present invention relates to a method for producing hEGF (human epidermal growth factor) which has the same activity as the wild form, in high concentration and with a high degree of purity. More specifically, the invention relates to an hEGF expression vector comprising a nucleic acid sequence coding for the polypeptide of sequence number 14; a host cell in which the expression vector has been genetically transformed; and a method for producing hEGF, comprising a step in which the expression vector is created and is genetically transformed in yeast from which the KEX1 gene is lacking. Using the method of the present invention, it is possible to produce a large volume of human derived EGF which has the same size and activity as human derived EGF, and this EGF can be used in various ways such as in medicine and cosmetics.