The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Aug. 10, 2012
Masazumi Kamohara, Tokyo, JP;
Hirotsugu Tanaka, Tokyo, JP;
Yukari Koya, Tokyo, JP;
Jun Takasaki, Tokyo, JP;
Atsuo Yonezawa, Tokyo, JP;
Eiji Yoshimi, Tokyo, JP;
Masazumi Kamohara, Tokyo, JP;
Hirotsugu Tanaka, Tokyo, JP;
Yukari Koya, Tokyo, JP;
Jun Takasaki, Tokyo, JP;
Atsuo Yonezawa, Tokyo, JP;
Eiji Yoshimi, Tokyo, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
[Task] To provide an anti-human NGF antibody or an antigen-binding fragment thereof that is excellent in safety by reducing the risk of side effects such as effects on a fetus and thrombus formation while maintaining high neutralizing activity, and to provide means for preventing or treating various diseases in which human NGF is involved in the formation of pathological conditions, by using the antibody or the antibody-binding fragment thereof. [Means for Resolution] An anti-human NGF antibody Fab' fragment comprising a heavy-chain variable region consisting of an amino acid sequence shown by SEQ ID NO:6 and a light-chain variable region consisting of an amino acid sequence shown by SEQ ID NO:4.