The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Mar. 24, 2011
Applicant:
Stephen Hamilton, Enfield, NH (US);
Inventor:
Stephen Hamilton, Enfield, NH (US);
Assignee:
Glycofi, Inc., Lebanon, NH (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12P 21/00 (2006.01); C12N 9/10 (2006.01); C12N 9/24 (2006.01);
U.S. Cl.
CPC ...
C12P 21/005 (2013.01); C12N 9/1051 (2013.01); C12Y 302/0113 (2013.01); C12N 9/2488 (2013.01);
Abstract
The present invention generally relates to methods of modifying the glycosylation structures of recombinant proteins expressed in fungi or other lower eukaryotes, to more closely resemble the glycosylation of proteins from higher mammals, in particular humans. The present invention also relates to novel enzymes and, nucleic acids encoding them and, hosts engineered to express the enzymes, methods for producing modified glycoproteins in hosts and modified glycoproteins so produced.