The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Dec. 19, 2008
Applicants:

Remco Kort, Amsterdam, NL;

Frank Henri Johan Schuren, Veenendaal, NL;

Roy Christiaan Montijn, Amersterdam, NL;

Inventors:

Remco Kort, Amsterdam, NL;

Frank Henri Johan Schuren, Veenendaal, NL;

Roy Christiaan Montijn, Amersterdam, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); C12Q 1/04 (2006.01); G01N 21/64 (2006.01); C12Q 1/06 (2006.01); G01N 21/80 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/04 (2013.01); G01N 21/6428 (2013.01); G01N 21/80 (2013.01);
Abstract

The invention relates to a method for real-time detection of viable microorganisms comprising: a. addition of a cell-permeable, phototautomeric compound to a micro-organism or other living cell; and b. measuring the fluorescent emission of said phototautomeric compound. Preferably the phototautomeric compound is salicylic acid, 2-hydroxy-1-naphtoic acid or 1-hydroxy-2-naphtoic acid. Further, the assay can he used to assess the antibiotic effect of a test compound. This test can be used as a high—throughput screening for compounds with antibiotic activity. Also part of the invention is the use of a cell permeable phototautomeric compound in a method for determining the viability of micro-organisms and for assessing the antibiotic effect of a test compound.


Find Patent Forward Citations

Kort, Remco. (2015). Real-time method for the detection of viable micro-organisms (U.S. Patent No. 8986946). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8986946

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