The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Apr. 15, 2010
Applicants:

Cherie L. Stabler, Coral Gables, FL (US);

Benjamin S. Harrison, Tobaccoville, NC (US);

Christopher A. Fraker, Hollywood, FL (US);

Eileen Pedraza, Coral Gables, FL (US);

Camillo Ricordi, Miami, FL (US);

Inventors:

Cherie L. Stabler, Coral Gables, FL (US);

Benjamin S. Harrison, Tobaccoville, NC (US);

Christopher A. Fraker, Hollywood, FL (US);

Eileen Pedraza, Coral Gables, FL (US);

Camillo Ricordi, Miami, FL (US);

Assignees:

University of Miami, Miami, FL (US);

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/00 (2006.01); A61P 41/00 (2006.01); A61K 9/00 (2006.01); A61L 15/44 (2006.01); A61L 15/18 (2006.01); A61L 27/54 (2006.01);
U.S. Cl.
CPC ...
A61L 15/44 (2013.01); A61L 15/18 (2013.01); A61L 27/54 (2013.01); A61L 2300/11 (2013.01); A61L 2300/602 (2013.01); A61L 2300/63 (2013.01);
Abstract

A composite for delivering extended-release of oxygen is disclosed. The composite can include a biocompatible polymeric support having a plurality of solid peroxide particles suspended therein. The polymer support can exhibit an oxygen tension value of at least 40 mmHg for a period of 14 days. The weight ratio of biocompatible polymeric support to solid peroxide particles can range from 1:1 to 99:1. Also disclosed is a method of using the composite to deliver oxygen to cells in both in vivo and in vitro environments.


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