The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Oct. 08, 2010
Applicants:

David Jackson, North Balwyn, AU;

Weiguang Zeng, Kensington, AU;

Inventors:

David Jackson, North Balwyn, AU;

Weiguang Zeng, Kensington, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/29 (2006.01); A61K 39/385 (2006.01); A61K 39/39 (2006.01); C07K 14/005 (2006.01); C07K 14/195 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 39/145 (2013.01); A61K 39/29 (2013.01); A61K 39/385 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55544 (2013.01); A61K 2039/57 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6075 (2013.01); C07K 14/005 (2013.01); C07K 14/195 (2013.01); C07K 19/00 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/18422 (2013.01); C12N 2770/24222 (2013.01); C12N 2770/24234 (2013.01);
Abstract

The present invention provides synthetic immunogenic lipopeptide molecules comprising co-linear T-helper and CTL epitopes, and methods for their production and use in the generation of primary and secondary immune responses, and for the vaccination of animal subjects against particular CTL epitopes. More particularly, the present invention provides highly soluble lipopeptides wherein the lipid moiety is attached to the terminal side-chain group of an internal lysine or lysine analog, preferably to the terminal side-chain group of an internal diamino acid residue. Preferably the internal lysine or lysine analog is positioned between the T-helper epitope and the CTL epitope.


Find Patent Forward Citations

Loading…